Ever wonder why constant carbs might be holding you back? mTOR drives growth (great in moderation), but chronic activation from high insulin promotes overgrowth—including in cancer cells. Fasting or low-carb periods activate AMPK, stimulates autophagy (cellularwhich cleanup). Balance both for better health! Educational info only—talk to your doctor before fasting/diet changes. #Autophagy #mTOR #AMPK #IntermittentFasting #CellularHealth | Center Stage Primary Care
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Video: mTOR Signaling and Cancer Progression
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mTOR will make you bigger: The mTOR pathway is a central regulator of metabolism with important roles in the function of tissues including liver, muscle, white and brown adipose tissue, and the brain. The activation of TORC1 activation is required for myofibrillar muscle protein synthesis and skeletal muscle hypertrophy in humans in response to both physical exercise and ingestion of certain amino acids or amino acid derivatives. Here is a very good lecture by David Sabatini about the regulation
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Protein, Leucine & mTOR: Balance for Longevity 🧬💪 mTOR is a master growth switch. Leucine-rich protein (and insulin) turns it on—great for muscle, recovery, and metabolic health. Turning it down at times—via fasting, lower protein windows, polyphenols, or exercise-induced AMPK—supports cellular repair, autophagy, and lifespan (seen across multiple model organisms). The playbook isn’t “always on” or “always off.” It’s strategic cycling: • Hit a leucine threshold (~2–3 g) with 30–50 g high-quali
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