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Part 2 of my Idiopathic Peripheral Neuropathy series. Once oral medications reach their ceiling, the strategy should shift — not just escalate. Topical therapies often provide meaningful relief with less systemic burden. Medical food supplements like Metanx or B-complex formulations may support metabolic pathways, but I view them as adjuncts rather than primary treatments. And for patients whose pain continues to limit function, neuromodulation is no longer experimental — it’s an evidence-suppor
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