McMaster University researchers have found not only how some viral infections cause severe tissue damage, but also how to reduce that damage. They have discovered how Type I interferon (IFN) stops the ...
In a recent study posted to the bioRxiv* preprint server, Canadian researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on interferon (IFN) ...
In a recent study posted to the medRxiv* preprint server, researchers assessed whether loss-of-function (pLOF) variants of type I interferon (IFN) immunity genes are associated with life-threatening ...
High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...
In their continuing work to limit the impact of COVID-19, Emory University researchers have, for the first time in nonhuman primates, studied how modulating the signaling of type 1 Interferon (IFN-I), ...
Adenosine deaminase 2 deficiency (DADA2) is an inborn error of immunity leading to systemic vasculitis, haematological manifestations, immune deficiency and/or autoimmunity. We report the case of a 26 ...
Antibody-binding of blood dendritic cell antigen 2 (BDCA2), which is expressed exclusively on plasmacytoid dendritic cells, suppresses the production of type I interferon that is involved in the ...
Elevated interferon alfa levels mark a subgroup of Sjögren disease, revealing immune changes years before diagnosis, and mice studies mirror these findings.
Researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from 'going rogue' and attacking the ...
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