Targeted protein degradation (TPD) is a rapidly advancing field with high potential in addressing proteotoxic stress and managing disease progression. TPD has generated a lot of interest in the last ...

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to ...

Many cancer drugs work by inhibiting the activity of proteins — the molecules that do most of the work in the cell. But some misbehaving proteins that turn normal cells cancerous are difficult to ...