In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader ...

A 44-year-old otherwise healthy man presents to an emergency department in Baltimore, noting that for the past 24 hours he has had a sharp pain in his chest that worsens when he breathes deeply. He ...

A man in his early 60s presents to the emergency department (ED) with a 1-day history of pleuritic central chest pressure. He has a history of a recent myocardial infarction (MI) that was treated with ...

Inflammation of the parietal pleura-outer, epithelial lining of the lungs is known as pleurisy (or pleuritis). The fast moving pain signals in the parietal pleura cause severe and local pain in the ...

THE intravenous administration of tetraethylammonium chloride to a patient acutely ill with thrombophlebitis and pulmonary infarction unexpectedly relieved the patient's severe pleuritic pain. As a ...