A researcher's guide to spatial transcriptomics: how sequencing- and imaging-based methods work, and how to choose a platform ...

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, ...

Spatial transcriptomics probe design shapes what any targeted experiment can detect. Explore how to compare pre-designed and ...

Researchers have developed Fullscope-seq, a long-read spatial transcriptomics platform that maps alternative transcript isoforms within intact tissues at single-cell resolution - opening new ...

Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.