Epithelial cell polarity is established along an apico-basal axis through coordinated activity of conserved protein complexes, notably the Par, Crumbs and Scribble modules. These complexes interface ...

Epithelial tissues define organ boundaries and perform selective barrier, transport and signalling functions. Their formation relies on the orchestration of cell polarisation, coordinated shape ...

Epithelial cells line the body’s surfaces to protect against physical damage, pathogens, and dehydration. These cells play key roles in absorbing nutrients and removing waste products, as well as ...

A distinct signaling pathway called TNF- drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF- program and become invasive ...