In the upper of the picture, the normal embryo goes through a key morphogenetic step during the transition from blastocyst to egg cylinder that epiblast cells marked by red are transformed into a ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

For the first time, stem cells typically considered restricted to forming body tissues spontaneously formed a yolk-sac-like structure in a model of the human embryo. Stem cell models of human embryos ...

A blastoid, a stem cell model system that allows scientists to study the nuances of human gastrulation. Credit: Laboratory of Stem Cell Biology and Molecular Embryology at The Rockefeller University ...

During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...