Description Microbial metabolism represents one of the most chemically diverse and functionally complex systems in nature. Despite decades of research, a ...

Deep in our cells, a wide range of processes are occurring constantly. These cellular processes rely on enzymes to act as catalysts and set off a series of molecular interactions. There are still many ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

Arren Bar-Even drove a new way to engineer metabolism; his former collaborators and students are continuing the work ...

The transformation of healthy cells into invasive colorectal tumors is an extraordinarily complex process involving numerous molecular mechanisms, according to cancer biologists in China who have ...

Folate coenzymes are pivotal for one-carbon transfers in nucleotide and amino acid metabolism. Microorganisms synthesise folate de novo, making the pathway an attractive target for antimicrobial and ...

Enzyme 'atlas' helps researchers decipher cellular pathways Biologists have mapped out more than 300 protein kinases and their targets, which they hope could yield new leads for cancer drugs ...

NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Researchers at Indiana University have identified a single enzyme in brain neurons that, when removed, sharply reduced the ...