Nature

Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces

Various technologies are currently available to quantify DNA methylation. However, rapid and simple methods for determining the DNA methylation status of CpG sites in genes still remain elusive. In ...
Nature

DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia

Fifty-seven placentas with or without associated preeclampsia and/or IUGR were collected from Vancouver BC Children's and Women's Hospital with informed consent from individuals, as was approved by ...
technologynetworks

In-solution Hybrid Capture of Bisulfite-converted DNA for Targeted Bisulfite Sequencing of 174 ADME Genes

DNA methylation is one of the most important epigenetic alterations involved in the control of gene expression. Bisulfite sequencing of genomic DNA is currently the only method to study DNA ...