Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

A team led by Professor Inkyung Jung from the Department of Biological Sciences at KAIST, working with Professor Yarui Diao’s ...

Article reviewed by Julía Crispim da Fontoura, a PhD candidate at the Federal University of Health Sciences of Porto Alegre, Brazil who uses organoids to study drug resistance. Stay up to date on the ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

3D cell cultures are no longer a futuristic idea. They’re already reshaping how we study diseases like cancer, offering more realistic models of how cells behave in the body. But despite their ...

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...

Developing chemotherapy drugs against breast cancer is costly, slow, and often inefficient, with more than 95% of screened drug candidates failing in patient trials. A new technique for 3D cell ...

There is growing use of three-dimensional (3D) cell culture models to attempt to reproduce cell-to-cell and cell-to-matrix interactions occurring in vivo. The goal is to create model systems for ...

Jai Prakash (left) is a Professor in the Department of Advanced Organ Bioengineering and Therapeutics at the University of Twente (Enschede, Netherlands), where he works with Postdoc Marcel Heinrich ...

Growing cells in three dimensions is critical for studying how tissues behave in the body, yet most laboratory platforms remain either too simple or too complex to use widely. Researchers now present ...